Dr. Steiling is an Assistant Professor of Medicine and Bioinformatics at Boston University. She sees patients in the Lung Nodule Clinic, multidisciplinary Thoracic Oncology Clinic and attends in the Medical Intensive Care Unit at Boston Medical Center. She oversees the Lung Cancer Screening Program and co-chairs the Lung Cancer Screening Steering Committee.
Dr. Steiling’s research focuses on in applying high-throughput genomic technologies to the diagnosis, treatment and prevention of lung diseases has been facilitated by my extensive training in both clinical pulmonary medicine and the analysis of gene expression datasets. Using the airway field of injury hypothesis, which posits that cigarette smoking induces molecular changes throughout the respiratory tract, I have studied alterations in the airway transcriptome that reflect the presence, susceptibility, and progression of smoking-induced lung diseases. I have used whole-genome expression profiling of the bronchial airway epithelium to describe the relationship between upper and lower airway gene expression, and leveraged this information to develop clinically-relevant biomarkers of lung cancer, COPD, and other diseases that affect the lung.